37 |  Patel, K.; Ahmed, Z. S. O.; Huang, X.; Yang, Q.; Barzegar, E. E.; Neslund-Dudas, C. M.; Mitra, B.; Elnady, F. A. E. M.; Ahn, Y. H.; Yang, H.; Liu, J.; Dou, Q. Discovering proteasomal deubiquitinating enzyme inhibitors for cancer therapy: lessons from rational design, nature and old drug reposition. Future Med. Chem. 2018, In press.

36 |  Kekulandara, D. N.; Nagi, S.; Seo, H.; Chow, C. S.; Ahn, Y. H. Redox-inactive peptide disrupting Trx1-Ask1 interaction for selective activation of stress signaling. Biochemistry. 2018, 57, 772–780.



35 |  Zhao, J.; Liu, J.; Lee, J. F.; Zhang, W.; VanHecke, G. C.; Gartung, A.; Gauldie, J.; Ahn, Y. H.; Lee, M. J. Sphingosine-1-phosphate receptor subtype 3 regulates TGF-β-mediated Sani1/E-cadherin pathway and lung adenocarcinoma progression. J. Biol. Chem. 2016291, 27343-27353.

34 Kekulandara, D. N.; Samarasinghe, K. T. G.; Munkanatta Godage, D. N. P.; Ahn, Y. H. Clickable glutathione using tetrazine-alkene bioorthogonal chemistry for detecting protein glutathionylation. Org. Biomol. Chem. 2016, In Print. Link


33 Gartung, A.; Zhao, J.; Chen, S.; Mottillo, E.; VanHecke, G. C.; Ahn, Y. H.; Maddipati, K. R.; Sorokin, A.; Granneman, J.; Lee, M. J. Characterization of eiscosanoids produced by adipocyte lipolysis: implication of cyclooxygenase-2 in adipose inflammation. J. Biol. Chem. 2016, 291, 16001-16010.

32 | Samarasinghe, K. T. G.; Munkanatta Godage, D. N. P.; Zhou, Y.; Ndombera, F. T.; Weerapana, E.; Ahn, Y. H. Identification of protein glutathionylation in response to glucose metabolism. Mol. Biosyst. 2016, 12, 2471-2480. Link


31 |  Ndombera, F. T.; VanHecke, G. C.; Nagi, S.; Ahn, Y. H. Carbohydrate-based Inducers of Cellular Stress for Targeting Cancer Cells. Bioorg. Med. Chem. Lett. 201626, 1452-1456. Link



30 |  Tu, Shun.; Guo, S. J.; Chen, C. S.; Liu, C. X.; Jiang, H. W.; Ge, F.; Deng, J. Y.; Zhou, Y. M.; Czajkowsky, D.; Li, Y.; Cole, P. A.; Ahn, Y. H.; Zhu, H.; Tao, S. C. YcgC Represents a New Protein Deacetylase Family in Prokaryote. eLife20154, e05322. PubMed Link

29 |  Samarasinghe, K. T. G.; Ahn, Y. H. Synthesizing Clickable Glutathione by Glutathione Synthetase Mutant for Detecting Protein Glutathionylation. SynLett. 201526, 285-293. Thieme Link


28 |  Wei, S.; Shalhout, S.; Ahn, Y. H.; Bhagwat, A. S. A Versatile New Tool to Label Abasic Sites in DNA and Inhibit Base Excision Repair. DNA Repair201527, 9-18. PubMed Link


27 |  Zhang, W.; Mottillo, E. P.; Zhao, J.; Gartung, A.; VanHecke, G. C.; Lee, J. F.; Maddipati, K. R.; Xu, H.; Ahn, Y. H.; Prola, R. L.; Granneman, J. G.; Lee, M. J. Adipocyte Lipolysis-stimulated Interleukin-6 Production Regulates Sphingosine Kinase 1 Activity J. Biol. Chem.2014289, 32178-32185. PubMed Link

26 |  Samarasinghe, K. T. G.; Munkanatta Godage, D. N. P.; VanHecke, G. C.; Ahn, Y. H. Metabolic Synthesis of Clickable Glutathione for Chemoselective Detection of Glutathionylation. J. Am. Chem. Soc. 2014136, 11566-11569. JACS Link


25 |  Zhang, Y.; Naidu, S. D.; Samarasinghe, K.; VanHecke, G. C.; Pheely, A.; Boronina, T. N.; Cole, R. N.; Benjamin, I. B.; Cole, P. A.; Ahn, Y. H.; Dinkova-Kostova, A. T. Inhibition of HSP90 by sulfhydryl-reactive sulfoxythiocarbamates. Brit. J. Cancer. 2014110, 71-82. BJC Link

24 |  Chiang, M. J.; Hobert, M. A.; Kalin, J. H.; Ahn, Y. H.; Giddens, J.; Amin, M. N.; Taylor, M. S.; Collins, S. L.; Chan-Li, Y.; Waickman, A.; Hsiao, P. Y.; Bolduc, D.; Leahy, D. J.; Horton, M. R.; Wang, L. X.; Powell, J. D.; Cole, P. A. An Fc Domain Protein-Small Molecule Conjugate as an Enhanced Immunomodulator. J. Am. Chem. Soc. 2014136, 3370-3373. JACS Link


23 |  Dancy, B. M.; Crump, N. T.; Peterson, D. J.; Mukherjee, C.; Bowers, E. M.; Ahn, Y. H.; Yoshida, M.; Zhang, J.; Mahadevan, L. C.; Meyers, D. J.; Boeke, J. D.; Cole, P. A. Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition. Chembiochem. 2012,13, 2113-2121. PubMed Link


22 |  Zhang, Y.; Ahn, Y. H.; Benjamin, I. J.; Honda, T.; Hicks, R. J.; Calabrese, V.; Cole, P. A.; Dinkova-Kostova, A. T. A novel role for sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway: HSF1-dependent upregulation of Hsp70. Chem. Biol. 201118, 1355-1361. (denote the contribution equally). PubMed Link

21 |  Smirnova, N. A.; Haskew-Layton, R. E.; Manuela, B.; Hushpulian, D. M.; Payappilly, J. B.; Speer, R. E.; Ahn, Y. H.; Rakhman, I.; Cole, P. A.; Pinto, J. T.; Ratan, R. R.; Gazaryan, I. G. Development of Neh2-Luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators. Chem. Biol. 201118, 752-765. PubMed Link

20 |  Collins, S. L.; Black, K. E.; Chan-Li, Y.; Ahn, Y. H.; Cole, P. A.; Powell, J. D.; Horton, M. R. Hyaluronan Fragments promote inflammation by down-regulating the anti-inflammatory A2a receptor. Am. J. Respir. Cell. Mol. Biol. 201145, 675-683. PubMed Link

19 |  Lee, J. J.; Lee, S. C.; Zhai, D.; Ahn, Y. H.; Yeo, H. Y.; Tan, Y. L.; Chang, Y. T. Bodipy-diacrylate imaging probes for targeted proteins inside live cells. Chem. Commun201147, 4508-4510. PubMed Link

18 |  Kim, Y. K.; Lee, J. S.; Bi. X.; Ha, H. H.; Ng, S. H.; Ahn, Y. H.; Lee, J. J.; Wagner, B. K.; Clemons, P. A.; Chang, Y. T. The binding of fluorophores to proteins depends on the cellular environment. Angew. Chem. Int. Ed. Engl. 201150, 2761-2763. PubMed Link


17 |  Ahn, Y. H.; Hwang, Y.; Liu, H.; Wang, X. J.; Zhang, Y.; Stephenson, K. K.; Boronina, T. N.; Cole, R. N.; Dinkova-Kostova, A. T.; Talalay, P.; Cole, P. A. Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc. Natl. Acad. Soc. USA. 2010107, 9590-9595. PubMed Link

16 |  Im, C. N.; Kang, N. Y.; Ha, H. H.; Bi, X.; Lee, J. J.; Park, S. J.; Lee, S. Y.; Vendrell, M.; Kim, Y. K.; Lee, J. S.; Li, J.; Ahn, Y. H.; Feng, B.; Ng, H. H.; Yun, S. W.; Chang, Y. T. A fluorescent rosamine compound selectively stains pluripotent stem cells. Angew. Chem. Intl. Ed2010,49, 7497-7500. PubMed Link

15 |  Cho, S. J.; Ahn, Y. H.; Maiti, K. K.; Dinish, U. S.; Fu, C. Y.; Thoniyot, P.; Olivo, M.; Chang, Y. T. Combinatorial synthesis of a triphenylmethine library and their application in the development of surface enhanced raman scattering (SERS) probes. Chem. Commun2010,46, 722-724. PubMed Link

14 |  Kim, Y. K.; Ha, H. H.; Lee, J. S.; Bi, X.; Ahn, Y. H.; Hajar, S.; Lee, J. J.; Chang, Y. T. Control of muscle differentiation by a mitochondria-targeted fluorophore. J. Am. Chem. Soc. 2010,132, 576-579. PubMed Link


13 |  Ahn, Y. H.; Lee, J. S.; Chang, Y. T. Selective human serum albumin sensor from the screening of a fluorescent rosamine library. J. Combi. Chem200810, 376-380. PubMed Link

12 |  Wagner, B. K.; Carrinski, H.; Ahn, Y. H.; Kim, Y. K.; Gilbert, T. J.; Fomina, D.; Schreiber, S. L.; Chang, Y. T.; Clemons, P. A. Small molecule fluorophores to detect cell-state switching in the context of high-throughput screening. J. Am. Chem. Soc2008130, 4208-4209. PubMed Link


11 |  Li, Q.; Min, J.; Ahn, Y. H.; Namm, J.; Kim, E. M.; Lui, R.; Ji, Y.; Wu, Z. H.; Wisniewski, T.; Chang, Y. T. Styryl-based potential in vivo imaging agents for beta-amyloid plaques.Chembiochem 20078, 1679-1687. PubMed Link

10 |  Min, J.; Lee, J. W.; Ahn, Y. H.; Chang, Y. T. Combinatorial synthesis of dapoxyl dyes and application to site specific probe for human serum albumin. J. Combi. Chem20079, 1079-1083. ResearchGate Link

09 |  Ahn, Y. H.; Chang, Y. T. Tagged small molecule library approach for facilitated chemical genetics. Acc. Chem. Res. 200740, 1025-1033. PubMed Link

08 |  Ahn, Y. H.; Lee, J. S.; Chang, Y. T. Combinatorial rosamine library and application to in vivo glutathione probe. J. Am. Chem. Soc2007129, 4510-4511. PubMed Link


07 |  Li, Q.; Kim, Y. K.; Namm, J.; Kulkarni, A.; Rosania, G.; Ahn, Y. H.; Chang, Y. T. RNA-selective, live cell imaging probes for studying nuclear structure and function. Chem. Biol.200613, 615-623. PubMed Link


6 |  Chi, Y.; Zhou, B.; Wang, W. Q.; Chung, S. K.; Kwon, Y. U.; Ahn, Y. H.; Chang, Y. T.; Tsujishita, Y.; Hurley, J. H.; Zhang, Z. Y. Biochemical characterization and substrate specificity of inositol polyphosphate 5-phosphatases synaptojanin and SHIP2. J. Biol. Chem. 2004279, 44987-44995. PubMed Link

5 |  Ahn, Y. H.; Chang, Y. T. Molecular evolution using intramolecular acyl migration on myo-inositol benzoates with thermodynamic and kinetic selectors. Chem. Eur. J. 200410, 3543-3547. PubMed Link

4 |  Ahn, Y. H.; Chang, Y. T. Molecular evolution on chiro-inositol dibenzoate using intramolecular acyl migration and selection by phenyl boronic acid. J. Combi. Chem. 20046, 293-296. PubMed Link


3 |  Ahn, Y. H.; Chung, S. K. A study on the effect of lanthanide ion coordination on the stereoselective synthesis of �-mannopyranosides. Bull. Kor. Chem. Soc. 200324, 116-118. PDF Link


2 |  Ahn, Y. H.; Chung, S. K. A study of benzene 1,2,4-trisphosphate derivatives as inositol 1,4,5-trisphosphate 3-kinase inhibitors. Bull. Kor. Chem. Soc. 200223, 515-517. PDF Link


1 |  Chung, S. K.; Kwon, Y. U.; Ahn, Y. H.; Jeong, T. H.; Chang, Y. T. A novel DAST-induced debenzylative cycloetherization in D-1,2-O-isopropylidene-3,4,5-tri-O-benzyl-myo-inositol.Bull. Kor. Chem. Soc. 200021, 274-276. PDF Link