Wayne State University

Aim Higher



College of Liberal Arts & Sciences
Department of Chemistry
Faculty Page
 
Jeremy Kodanko
Title Associate Professor
Division Organic (Inorganic)
Education B.S., University of Wisconsin-Madison, 1998
Ph.D., University of California-Irvine, 2003
NIH Postdoctoral Fellow, Massachusetts Institute of Technology, 2003-6
Office Chem 261
Phone (313)577-9043
E-Mail
Group http://chem.wayne.edu/kodankogroup


Research in the Kodanko laboratory is at the interface of organic, inorganic and medicinal chemistry. We are interested in harnessing the power of metal complexes for biological applications. Projects currently being conducted in the Kodanko laboratory span across many subdisciplines of chemistry research including organic and inorganic synthesis, catalysis, kinetic and mechanistic studies, coordination chemistry, enzyme inhibition and cell biology. Recent interests have focused on the development of light-activated compounds for biological research applications, and as potential therapeutics.






REPRESENTATIVE PUBLICATIONS

Li, A.; White, J. K.; Arora, K.; Herroon, M. K.; Martin, P. D.; Schlegel, H. B.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Selective Release of Aromatic Heterocycles from Ruthenium Tris(2-pyridylmethyl)amine with Visible Light" Inorg. Chem. 2016, 55, 10.

Ramalho, S. D.; Sharma, R.; White, J. K.; Aggarwal, N.; Chalasani, A.; Sameni, M.; Moin, K.; Vieira, P. C.; Turro, C.; Kodanko, J. J.; Sloane, B. F. "Imaging sites of inhibition of proteolysis in pathomimetic human breast cancer cultures by light-activated ruthenium compound" PLoS One 2015, 10, e0142527/1.

Sharma, R.; Knoll, J. D.; Ancona, N.; Martin, P. D.; Turro, C.; Kodanko, J. J. "Solid-Phase Synthesis as a Platform for the Discovery of New Ruthenium Complexes for Efficient Release of Photocaged Ligands with Visible Light" Inorg. Chem. 2015, 54, 1901.

Respondek, T.; Sharma, R.; Herroon, M. K.; Garner, R. N.; Knoll, J. D.; Cueny, E.; Turro, C.; Podgorski, I.; Kodanko, J. J. "Inhibition of Cathepsin Activity in a Cell-Based Assay by a Light-Activated Ruthenium Compound" ChemMedChem 2014, 9, 1306.

Respondek, T.; Garner, R. N.; Herroon, M. K.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Light Activation of a Cysteine Protease Inhibitor: Caging of a Peptidomimetic Nitrile with RuII(bpy)2" J. Am. Chem. Soc. 2011, 133, 17164.



DEPARTMENT OF CHEMISTRY ©
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5101 Cass Ave, Detroit, MI 48202
Phone: (313) 577-7784    Fax: (313) 577-8822

image to WSU giving program link
image to WSU giving program link