Wayne State University

Aim Higher

College of Liberal Arts & Sciences
Department of Chemistry
Faculty Page
Jeremy Kodanko
Title Associate Professor & Associate Chair
Division Organic (Inorganic)
Education B.S., University of Wisconsin-Madison, 1998
Ph.D., University of California-Irvine, 2003
NIH Postdoctoral Fellow, Massachusetts Institute of Technology, 2003-6
Office Chem 261
Phone (313)577-9043
Group http://chem.wayne.edu/kodankogroup

Research in the Kodanko laboratory is at the interface of organic, inorganic and medicinal chemistry. We are interested in harnessing the power of metal complexes for biological applications. Projects currently being conducted in the Kodanko laboratory span across many subdisciplines of chemistry research including organic and inorganic synthesis, catalysis, kinetic and mechanistic studies, coordination chemistry, enzyme inhibition and cell biology. Recent interests have focused on the development of light-activated compounds for biological research applications, and as potential therapeutics.


Li, A.; White, J. K.; Arora, K.; Herroon, M. K.; Martin, P. D.; Schlegel, H. B.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Selective Release of Aromatic Heterocycles from Ruthenium Tris(2-pyridylmethyl)amine with Visible Light" Inorg. Chem. 2016, 55, 10.

Ramalho, S. D.; Sharma, R.; White, J. K.; Aggarwal, N.; Chalasani, A.; Sameni, M.; Moin, K.; Vieira, P. C.; Turro, C.; Kodanko, J. J.; Sloane, B. F. "Imaging sites of inhibition of proteolysis in pathomimetic human breast cancer cultures by light-activated ruthenium compound" PLoS One 2015, 10, e0142527/1.

Sharma, R.; Knoll, J. D.; Ancona, N.; Martin, P. D.; Turro, C.; Kodanko, J. J. "Solid-Phase Synthesis as a Platform for the Discovery of New Ruthenium Complexes for Efficient Release of Photocaged Ligands with Visible Light" Inorg. Chem. 2015, 54, 1901.

Respondek, T.; Sharma, R.; Herroon, M. K.; Garner, R. N.; Knoll, J. D.; Cueny, E.; Turro, C.; Podgorski, I.; Kodanko, J. J. "Inhibition of Cathepsin Activity in a Cell-Based Assay by a Light-Activated Ruthenium Compound" ChemMedChem 2014, 9, 1306.

Respondek, T.; Garner, R. N.; Herroon, M. K.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Light Activation of a Cysteine Protease Inhibitor: Caging of a Peptidomimetic Nitrile with RuII(bpy)2" J. Am. Chem. Soc. 2011, 133, 17164.

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