Wayne State University

Aim Higher

College of Liberal Arts & Sciences
Department of Chemistry
Faculty Page
Long Luo
Title Assistant Professor
Division Analytical
Education B.S., Beijing University of Aeronautics and Astronautics, 2009
Ph.D., University of Utah, 2014
Postdoctoral Fellow, University of Texas at Austin 2014-2017
Office Chem 383
Phone (313)577-0690
Group http://www.clas.wayne.edu/luogroup

Research in the Luo group is focused on exploring new frontiers in electrocatalytic and electroanalytical sciences. Key challenges we aim to address include selective electroreduction of carbon dioxide (CO2), single nanoparticle electrochemistry, and low cost point-of-care diagnostics.

(1) Selective Electrocatalysis: Increasing emission of CO2 gas from burning fossil fuels is becoming a serious global issue. Electrochemical reduction of CO2 is one promising solution because it can potentially convert CO2 into chemicals with economic value. However, the lack of product selectivity is a big challenge. Multiple products including undesired by-products are commonly yielded during CO2 electroreduction. The poor product selectivity causes low energy efficiency. We are developing new strategies to achieve selective electroreduction and building model catalysts for understanding the mechanisms.

(2) Single Nanoparticle Electrochemistry: Nanoparticles have attracted the attention of researchers due to their unique properties that emerge at the nanometer length scale. The development of high-performance functional nanoparticles requires in-depth fundamental understandings of their activities. However, current analytical techniques mostly depend on ensemble-averaged measurements so that interesting stochastic properties of nanoparticles are buried by the averaging effect of these measurements. We are developing new electrochemical platforms for single nanoparticle analysis to gain new knowledge about the dynamics of nanoparticle catalysts.

(3) Electrochemical Biosensors for Point-of-Care Testing: Point-of-care testing (POCT) is to perform biochemical testing at or near the site of patient care whenever the medical care is needed. One foremost challenge is the high cost and low long-term stability of bioreagents used in the POCT devices, in particular antibodies. One potential solution is to develop polymer-based "artificial antibodies" using molecular imprinting technology. However, neither the binding affinity nor the recognition specificity of artificial antibodies is comparable to these of natural antibodies at present. We are developing new artificial antibody-based electrochemical biosensors to address these challenges.


  1. Luo, L.; Duan, Z.; Li, H.; Kim, J.; Henkelman, G.; Crooks, R. M. Tunability of the Adsorbate Binding on Bimetallic Alloy Nanoparticles for the Optimization of Catalytic Hydrogenation. J. Am. Chem. Soc., 2017, 139 (15), pp 5538-5546.
  2. Luo, L.; Zhang, L.; Duan, Z.; Henkelman, G.; Crooks, R. M. Efficient CO Oxidation using Dendrimer-Encapsulated Pt Nanoparticles Activated with <2% Cu Surface Atoms, ACS Nano, 2016, 10, 8760-8769.
  3. Luo, L.; Li, X.; Crooks, R. M. Low-Voltage Origami-Paper-Based Electrophoretic Device for Rapid Protein Separation, Anal. Chem., 2014, 86, 12390-12397.
  4. Luo, L.; White, H. S. Electrogeneration of Single Nanobubbles at Sub-50-nm-Radius Platinum Nanodisk Electrodes. Langmuir, 2013, 29, 11169-11175.

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5101 Cass Ave, Detroit, MI 48202
Phone: (313) 577-7784    Fax: (313) 577-8822

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