Lee, T and Feig, AL (2007) The RNA Binding
Protien Hfq Interacts Specifically with tRNAs, RNA, submitted for publication.
Lee, T and Feig, AL (2007) Thermodynamids
of RNA:Protein Complexes as Exemplified by Escherichia coli Hfq. In Non-Protein Coding RNAs.
Nils Walter, Sarah Woodson and Robert Batey, Eds. Springer Verlag,
Heidelberg. in preparation.
Feig, AL. (2007) Applications of isothermal titration calorimetry in RNA biochemistry and biophysics. Biopolymers, DOI:10.1002/bip.20816 [pubmed] [PDF]
2006
Mikulecky, PJ and Feig, AL. (2006) Heat Capacity Changes Associated with DNA Duplex Formation: Salt- and Sequence-Dependent Effects. Biochemistry, 45, 605-616. [Pubmed] [PDF]
Mikulecky, PJ and Feig, AL. (2006) Heat Capacity Changes Associated with Nucleic Acid Folding. Biopolymers, 81, 38 - 58. [Pubmed] [PDF]
Kerzmann, A and Feig, AL. (2006) Cholesterol, It's Not Just For Heart Disease Anymore. ACS Chemical Biology, 1, 141 - 144. [Pubmed] [PDF]
Mikulecky, PJ, Kaw, M, Brescia, C, Takach, JC,
Sledjeski, D, and Feig, AL. (2004) E. coli Hfq Has Distinct Interaction
Surfaces for DsrA, rpoS and polyA RNAs. Nat. Struct. Mol. Biol. 11,
1206-1214. [Pubmed]
[PDF]
Mikulecky, PJ and Feig, AL. (2004) Heat Capacity Changes in RNA
Folding: Application of Perturbation Theory to Hammerhead Ribozyme Cold
Denaturation Nucl. Acids Res. 32,
3967 – 3976. [Pubmed]
[PDF]
Takach, J, Mikulecky, PJ, Feig, AL (2004) Salt–dependent Heat Capacity
Changes for RNA Duplex Formation. J.
Am. Chem. Soc. 126, 6530 – 6531. [Pubmed]
[PDF]
Mikulecky, PJ, Takach, J, and Feig, AL. (2004) Entropy–driven Folding
of an RNA Helical Junction: Isothermal Titration Calorimetric Analysis
of the Hammerhead Ribozyme. Biochemistry,
43, 5870 – 5881. [Pubmed]
[PDF]
Feig, AL. (2004) Challenge Your Teaching. Nature Struct. Mol. Biol. 11,
16 – 19. [Pubmed]
[PDF]
Brescia, CC, Mikulecky, PJ, Feig, AL, and Sledjeski, DD. (2003) Identification of the Hfq binding site on DsrA RNA: Hfq binds without altering DsrA secondary structure. RNA 9, 33 – 43. [Pubmed] [PDF]
Bhattacharyay, S, Kerzmann, A, and Feig, AL. (2002) Fluorescent Analogs of UDP–Glucose and Their Use in Characterizing Substrate Binding by Toxin A from Clostridium difficile. Eur. J. Biochem. 269, 3425 – 3432. [Pubmed] [PDF]
Feig, AL and Jabri, E. (2002) Incorporation of
Bioinformatics
Exercises into the Undergraduate Biochemistry Curriculum. Biochem. and
Mol. Biol. Ed. 30, 224 – 231. [Pubmed] [PDF]
Feig, AL. (2002) Ribozymes and RNA Catalysis. In The Encyclopedia of
Catalysis. Istavan Horvath, Ed. John Wiley & Sons. New York; Vol 6.
85 – 116.
(Web publication at:
http://www.mrw.interscience.wiley.com/enccat/articles/eoc182/frame.html.)
Mikulecky, PJ and Feig, AL. (2002) Cold Denaturation of the Hammerhead
Ribozyme. J. Am. Chem. Soc.
124, 890 – 891. [Pubmed]
[PDF]
Feig, AL. (2000) The Use of Manganese as a Probe for
Elucidation the Role of Magnesium Ions in Ribozymes. Metal Ions in
Biological Systems; Vol. 37. H. Sigel and A. Sigel Ed.; Marcel
Dekker,
New York; p. 157 – 182. [PubMed]
O’Rear, J, Wang, SL, Feig, AL, Uhlenbeck, OC, Herschlag, D. (2001) Comparison of the Hammerhead Cleavage Reactions Stimulated by Monovalent and Divalent Cations, RNA, 5, 537 – 545. [Pubmed] [PDF]
Feig, AL, Panek, M, Horrocks, WD, Jr., Uhlenbeck, OC.
(1999) Probing the Binding of Tb(III) and Eu(III) to the Hammerhead
Ribozyme by Luminescence Spectroscopy. Chem. and Biol. 6, 801 – 810. [Pubmed]
[PDF]
Feig, AL, Uhlenbeck, OC. (1999) The Role of Metal Ions in RNA
Biochemistry. In The RNA World; Second ed.; T. Cech, R. Gesteland and
J. Atkins, Ed.; Cold Spring Harbor Laboratory Press: Cold Spring
Harbor, NY, 287 – 320.
Feig, AL, Ammons, GE, Uhlenbeck, OC. (1998) Cryoenzymology of the
Hammerhead Ribozyme. RNA 4,
1251 – 1258. [Pubmed]
[PDF]
Feig, AL, Scott, WG, Uhlenbeck, OC. (1998) Inhibition of the Hammerhead
Ribozyme Cleavage Reaction by Site–Specific Binding of Tb(III). Science
279, 81 – 84. [Pubmed]
[PDF]
Ph.D.
Thesis Work (with Prof. Stephen Lippard)
Feig, AL, Masschelein, A, Bakac, A, Lippard, SJ. (1997)
Kinetic Studies of the Reactions of Carboxylate – Bridged Diiron(II)
Complexes with Dioxygen to Form (mu–Oxo)diiron(III) Products. J. Am.
Chem. Soc. 119, 334 – 342. [Pubmed] [PDF]
Feig, AL, Bautista, M, Lippard, SJ. (1996) A Carboxylate–Bridged
Non–Heme Diiron Dinitrosyl Complex. Inorg.
Chem. 35, 6892 – 6898. [Pubmed]
[PDF]
Feig, AL, Becker, M, Schindler, S, van Eldik, R, & Lippard, SJ.
(1996) Mechanistic Studies on the Formation and Decay of Diiron(III)
Peroxo Complexes. Inorg. Chem. 35,
2590 – 2601. [Pubmed]
[PDF]
Feig, AL, Lippard, SJ. (1994) Mechanistic Studies on the Reaction of
Dioxygen with Diiron(II) Compounds to Form (mu–Peroxo)diiron(III)
Complexes. J. Am. Chem. Soc.
116, 8410 – 8411. [Pubmed] [PDF]
Feig, AL, Lippard, SJ. (1994) Reactions of Non–Heme Iron(II) Centers
with Dioxygen in Biology and Chemistry. Chem. Rev. 94, 759 – 805.
[Pubmed] [PDF]
Liu, KE, Feig, AL, Goldberg, DP, Watton, SP, Lippard, SJ. (1993)
Methane Monooxygenase: Models and Mechanism. In The Activation of
Dioxygen and Homogeneous Catalytic Oxidation, Barton, D.H.R. et al.,
Eds.; Plenum: New York, p. 301 – 320.
Undergraduate
Research
Feig, AL, Thederahn, T, Sigman, DS. (1988) The
Mutagenicity of the Nuclease Activity of the 1,10 Phenanthroline –
Copper Ion. Biochem. Biophys. Res.
Comm. 155, 338 – 343. [Pubmed]
[PDF]
