Wayne State University

Aim Higher

College of Liberal Arts & Sciences
Department of Chemistry
Mass Spectrometry Mgr. Profile
Lew Hryhorczuk, Ph.D.
Title Laboratory Manager
Location Mass Spectrometry Core Facility
Lumigen Instrumentation Center
A. Paul Schaap Chemistry Building
Education B.S., Wayne State University, 1962
M.S., Wayne State University, 1965
Ph.D., University of Illinois Urbana-Champaign, 1972
Office Chem 37.1
Phone (313) 577-7788

Dr. Hryhorczuk's interests reside with the attainment and interpretation of mass spectrometric data for metal complexes, synthetic and natural organic compounds, and molecules of biological interest and biochemical activity. He particularly enjoys confirming chemical composition and elucidation of structural features using high resolution mass spectrometry.


F. D. Lesh, M. M. Allard, R. Shanmugam, L. M. Hryhorczuk, J. F. Endicott, H. B. Schlegel, C. N. Verani "Investigation of the Electronic, Photosubstitution, Redox, and Surface Properties of New Ruthenium(II)-Containing Amphiphiles", Inorg. Chem., 2011, 50, 969-977.

A. A. Campanali, T. D. Kwiecien, L. Hryhorczuk, J. J. Kodanko "Oxidation of glutathione by [FeIV(O)(N4Py)]2+: Characterization of an [FeIII(SG)(N4Py)]2+ intermediate", Inorg. Chem., 2010, 49, 4759-4761.

N. D. Jabre, L. Hryhorczuk, J. J. Kodanko: "Stability of a Ferryl-Peptide Conjugate is Controlled by a Remote Substituent", Inorg. Chem., 2009, 48, 8078-8080.

S. Hindo, M. Frezza, D. Tomco, M. J. Heeg, L. Hryhorczuk, B. R. McGarvey, Q. P. Dou, C. N. Verani: "Metals in anticancer therapy: Copper(II) complexes as inhibitors of the 20S proteasome" European Journal of Medicinal Chemistry, 2009, 44, 4353-4361.

F. D. Lesh; S. S. Hindo, M. M. Allard, P. Jain, B. Peng, L. Hryhorczuk, C. N. Verani: "On the Effect of Coordination and Protonation Preferences in the Amphiphilic Behavior of Metallosurfactants with Asymmetric Headgroups" European Journal of Inorganic Chemistry, 2009, 345-356.

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5101 Cass Ave, Detroit, MI 48202
Phone: (313) 577-7784    Fax: (313) 577-8822

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