Wayne State University

Aim Higher

College of Liberal Arts & Sciences
Department of Chemistry
X-Ray Crystallography Adjunct Faculty
Philip Martin, Ph.D.
Title X-Ray Facility Manager
Location Lumigen Instrumentation Center
A. Paul Schaap Chemistry Building
Education Northern Michigan University, Chemistry, Biology, B.S. 1967
Northern Michigan University, Chemistry, M.A. 1970
Wayne State University, Biochemistry, Ph.D. 1978
Michigan State University, Post-Doctoral, 1978-1981
Office Chem 65
Phone (313) 577-2587

Dr. Martin is an expert in both small and macro-molecule X-ray crystallography. From 2001-2009, he managed the Advanced Laboratory for Macromolecular Crystallography at the Wayne State University School of Medicine. His primary responsibilities were to perform crystallography and refine enzyme structure. Through his own initiative, he developed and taught a graduate level X-Ray Crystallography course, allowing student to collect and interpret their crystal structures. Summer 2013, he will co-teach the X-Ray diffraction workshop with Dr. Ron Baird. His doctoral research earned him the DeVlieg Foundation Graduate Fellowship.


C. Purcarea, P. D. Martin, J. F. Vickery, H. I. Guy, B. F. P. Edwards, D. R. Evans, "Cloning, expression and preliminary X-ray analysis of the dihydroorotase from the hyperthermophilic bacterium Aquifex aeolicus," Acta Cryst., D58, 154-156 (2002).

B. C. Logsdon, J. F. Vickery, P. D. Martin, G. Proteasa, J. I. Koepke, S. R. Terlecky, Z. Wawrzak, M. A. Winters, T. C. Merigan, L. C. Kovari, "Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity," J.Virol., 78, 3123-3132 (2004).

P. D. Martin, C. Purcarea, P. Zhang, A. Vaishnav, S. Sadecki, H. I. Guy-Evans, D. R. Evans, B. F. Edwards, "The crystal structure of a novel, latent dihydroorotase from Aquifex aelicus at 1.7A resolution," J. Mol. Biol., 348, 535-547 (2005).

J. Ye, A. Kandegedara, P. D. Martin, B. P. Rosen, "Crystal structure of the Staphylococcus aures pI258 CadC Cd(II)/Pb(II)/Zn(II)-responsive repressor," J. Bacteriol., 187, 4217-4221 (2005).

P. D. Martin, J. F. Vickery, G. Proteasa, Y. L. Jimenez, Z. Wawrzak, M. A. Winters, T. C. Merrigan, L. C. Kovari Knisley, "Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target," Structure, 13, 1887-1895 (2005).

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5101 Cass Ave, Detroit, MI 48202
Phone: (313) 577-7784    Fax: (313) 577-8822

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