Wayne State University

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College of Liberal Arts & Sciences
Department of Chemistry
L.I.C. - Mass Spectrometry Facilities Instrumentation
 

Mass Spectrometry Instrumentation

  Agilent 7700x ICP-MS

  • Metals analysis
  • Mid ppt to low ppb detection range
  • Option to detect in four different gas modes to gain optimum detection of multiple metals or interferences in a sample
  • Autosampler can hold 21, 50 mL falcon tubes and 180, 15 mL falcon tubes





 Shimadzu 8040 LC-Triple Quadrupole MS with PDA and Fluorescence Detection

  • Nexera X2 LC-30AD UHPLC system with a binary solvent system
  • ESI triple quadrupole mass spectrometer
  • SPD-M30A diode array detector
  • RF-20A XS fluorescence detector
  • Quantitative analysis or structural elucidation of small molecules
  • Mid ppt to low ppb detection limits
  • Mass Range: 50 – 2000 Da
  • Temperature controlled autosampler holds 324, 2 mL RAM vials
  • Column oven
  • Acquired through Shimadzu Grant.





  Thermo Scientific Altis LC-Triple Quadrupole MS

  • UltiMate 3000 UHPLC System with a binary solvent system which allows 4 different mobile phases, but only 2 at a time.
  • TSQ Altis ESI triple quadrupole mass spectrometer
  • Online concentration capabilities
  • Online concentration detection range in low ppt
  • Standard detection range mid ppt to low ppb
  • Mass Range: 5 – 2000 Da
  • Temperature controlled autosampler holds 162, 2 mL RAM vials, and 30, 10 mL vials and column oven
  • Run by laboratory staff only and primarily used for large projects





  Thermo Scientific LTQ Orbitrap XL with Nano LC and HPLC capabilities

  • High resolution mass spectrometer.
  • Resolution 60,000 at m/z 400 at a scan rate of 1 Hz
  • Up to 100,000 resolution
  • External calibration and lock mass for 1 ppm error.
  • Easy nano LC 1200
  • Waters Alliance HT 2795 HPLC with temperature controlled autosampler which holds 144, 2 mL RAM vials and column oven.
  • Quaternary pump up to 4,500 psi.
  • Mass Range
  • Linear Ion trap: 50-2000 m/z
  • Orbi-Trap: 200-4000 m/z
  • Sensitivity sub-femtomol range for peptides





  Bruker UltrafleXtreme MALDI-TOF/TOF

  • 300-350 kDa mass range with linear mode.
  • 300-6 kDa mass range with reflection mode and LIFT fragmentation.
  • CID or LID to analyze structure of proteins, RNA/DNA, and polymers.
  • FlexImaging for MALDI Imaging Mass Spectrometry.
  • BioTools for protein identification on Mascott database.
  • BioTyper for bacteria culture Identification.
  • SCiLs software package for 3D imaging and statistical analysis.





  Waters 2695/ZQ

  • Waters 2695 HPLC with temperature controlled autosampler which holds 120, 2 mL RAM vials and column oven.
  • 4500 psi maximum pressure quaternary pump.
  • ESI source with quadrupole analyzer from 50-2000 Da.
  • Source fragmentation by adjustable cone voltage.
  • Nominal mass accuracy for direct injection or chromatographic analysis.
  • 20 ng/mL to 10 μg/mL; Acetonitrile, Methanol, Water, or Isopropanol.





  Agilent 6890/5973 - Semivolatiles

  • Automatic Liquid Sampler holds 100, 2 mL RAM vials.
  • EI source and quadrupole analyzer from 10-600 Da
  • Rxi-5ms column for walk up analysis of organic reactions and quantitative analysis of semivolatiles.
  • Chemstation software and NIST database searching of fragmentation patterns.
  • Optional CDS8000 Thermal Desorption, Purge and Trap, and Pyrolyzer.





  Agilent 6890/5973 - Volatiles

  • EI source and quadrupole analyzer from 10-600 Da or FID.
  • Restek RTX-Volatiles column
  • Chemstation software and NIST database searching of fragmentation patterns.
  • Optional CDS8000 Thermal Desorption, Purge and Trap, and Pyrolyzer.
  • Optional Solatek 72 Purge and Trap autosampler with Velocity XPT Concentrator.
  • Optional manual SPME analysis.





  CDS8000 Concentrator

  • Manual Purge and Trap.
  • Manual thermal desorption tube sampling from active air sampling unit.
  • Bulk headspace analysis options:
  • 10 x 9.5 cm Large BDHS
  • 13 x 3 cm (a silanized steel tray is available that sits in the center of the tube long ways, for height of 1.5 cm)
  • 15 x 1.5 cm testube sampler
  • Cryofocusing available.





  Solatek 72 Purge and Trap with Velocity XPT Concentrator

  • 72 vial autosampler for 40 mL purge and trap vials.
  • In vial purge with heated sampler and stirring for soils and sludges.
  • Add 0-20 mL of water before sampling vapor.
  • 10 mL purge and trap liquid sampling sparging vessel.
  • 3 Optional internal standard or calibrant addition vials online.





  Perkin Elmer Clarus 580/Turbomatrix 40 Headspace GC-FID-ECD

  • 40 vial autosampler for headspace analysis.
  • Preheats samples during GC run to save time.
  • Flame Ionization Detector and Electron Capture Detectors available.
  • Minimum sample temperature of 35 °C.





  Waters 2695/996 PDA

  • Waters 2695 HPLC with 120 sample autosampler with column oven.
  • 4500 psi maximum pressure quaternary pump.
  • UV detector with Empower software package for quantitative analysis.

DEPARTMENT OF CHEMISTRY ©
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5101 Cass Ave, Detroit, MI 48202
Phone: (313) 577-7784    Fax: (313) 577-8822

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