Pflum Group Laboratory
Bioorganic Chemistry

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Mary Kay H. Pflum
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Newly Renovated Pflum Lab

Open Position: Postdoctoral Research Associate

A.Paul Schaap Chemistry Building Tour

 Latest News

Geetha's paper reporting the ELISA-based HDAC activity assay for Characterization of Isoform-Selective Inhibitors was published at Journal of Biomolecular Screening ...more>>

Fouda's paper was chosen as a VIP at Angewandte Chemie International Edition ...more>>

Ahmed E. Fouda's paper reporting a cell permeable ATP analog was published at Angewandte Chemie International Edition ...more>>

Inosha Gomes joined the lab ...more>>



Mary Kay H. Pflum, Ph.D.
Associate Professor of Chemistry

B.A. Chemistry, Carleton College, 1992
Ph.D. Bioorganic Chemistry, Yale University, 1999
NIH Post-doctoral Fellow in Chemical Biology, Harvard University, 2001

Dr. Pflum received a B.A. degree from Carleton College working with Jerry Mohrig in physical organic chemistry.  In Ph.D. training at Yale Univeristy with Alanna Schepartz, she worked on several bioorganic projects focusing on phosphoproteins and transcription factors.   In an NIH post-doctoral position at Harvard University with Stuart Schreiber, she worked on chemical biology and cell biology projects focusing on histone deacetylase proteins.  Dr. Pflum joined the faculty at Wayne State University in 2001 with a research program at the interface of Chemistry and Biology focusing on two cancer-related proteins - kinase and histone deacetylase enzymes. The multi-disciplinary research in her laboratory combined the fields of organic synthesis, biochemistry, enzymology, molecular biology, analytical chemistry, and cell biology. 

Positions and Honors
1996   Pre-doctoral Fellowship, American Chemical Society, Yale University    
1996   Pre-doctoral Fellowship, Lucille E. Dox Fellowship, Yale University                     
1999   Post-doctoral Fellowship, National Institute of Health, Harvard University           
2002   Research Innovation Award, Research Corporation, Wayne State University
2007   Teaching award, College of Liberal Arts and Science, Wayne State University
2008   President’s Award for Excellence in Teaching, Wayne State University
2008   Scientific Member, Barbara Ann Karmanos Cancer Institute
2010   Career Development Chair, Wayne State University
2012   Co-chair of the Bioorganic Chemistry Gordon Research Conference, Andover, NH
2014   Permanent Member of the NIH SBCB study section, National Institutes of Health

Research Funding
National Institutes of Health (GM079529 and GM067657)
National Science Foundation (CHE-130649)





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